BAIT
KCNMA1
5730414M22Rik, BKCa, MaxiK, Slo, Slo1, mSlo, mSlo1, RP24-486D21.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
GO Process (33)
GO Function (8)
GO Component (17)
Gene Ontology Biological Process
- adult walking behavior [IMP]
- auditory receptor cell differentiation [IMP]
- cell maturation [IMP]
- cellular potassium ion homeostasis [ISO]
- circadian rhythm [IMP]
- eye blink reflex [IMP]
- locomotor rhythm [IMP]
- micturition [IMP, ISO]
- negative regulation of cell volume [IMP, ISO]
- neuromuscular process controlling balance [IMP]
- neuronal action potential [IMP]
- positive regulation of apoptotic process [ISO]
- potassium ion transmembrane transport [IBA, IGI, ISO]
- potassium ion transport [IDA, ISO]
- protein homooligomerization [IDA]
- protein homotetramerization [ISO]
- regulation of aldosterone metabolic process [IMP]
- regulation of ion transmembrane transport [IMP]
- regulation of membrane potential [IDA, IMP, ISO]
- regulation of vasodilation [ISO]
- relaxation of vascular smooth muscle [IMP]
- response to calcium ion [ISO]
- response to carbon monoxide [ISO]
- response to corticosteroid [ISO]
- response to estrogen [ISO]
- response to hypoxia [IDA, ISO]
- response to osmotic stress [ISO]
- response to pH [ISO]
- saliva secretion [IGI]
- sensory perception of sound [IMP]
- smooth muscle contraction involved in micturition [IMP, ISO]
- synaptic transmission [IMP]
- vasodilation [IMP]
Gene Ontology Molecular Function- actin binding [ISO]
- calcium-activated potassium channel activity [IDA, IGI, IMP, ISO]
- large conductance calcium-activated potassium channel activity [IDA, IMP, ISO]
- potassium channel activity [IGI, IMP]
- protein binding [IPI]
- protein complex binding [ISO]
- protein homodimerization activity [ISO]
- voltage-gated potassium channel activity [IDA, IMP, ISO]
- actin binding [ISO]
- calcium-activated potassium channel activity [IDA, IGI, IMP, ISO]
- large conductance calcium-activated potassium channel activity [IDA, IMP, ISO]
- potassium channel activity [IGI, IMP]
- protein binding [IPI]
- protein complex binding [ISO]
- protein homodimerization activity [ISO]
- voltage-gated potassium channel activity [IDA, IMP, ISO]
Gene Ontology Cellular Component
- apical plasma membrane [IDA, ISO]
- caveola [ISO]
- cell [IMP]
- cytoplasm [IDA]
- dendrite [ISO]
- endoplasmic reticulum [IDA]
- external side of plasma membrane [IDA, ISO]
- extracellular vesicular exosome [ISO]
- integral component of membrane [IC, IDA, ISO]
- neuronal cell body [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [IDA, ISO]
- postsynaptic membrane [IDA]
- presynaptic active zone membrane [ISO]
- protein complex [ISO]
- terminal bouton [IDA]
- voltage-gated potassium channel complex [IGI, ISO]
Mus musculus
PREY
HSPA8
2410008N15Rik, Hsc70, Hsc71, Hsc73, Hsp73, Hspa10
heat shock protein 8
GO Process (10)
GO Function (13)
GO Component (18)
Gene Ontology Biological Process
- ATP catabolic process [IDA, ISO]
- chaperone mediated protein folding requiring cofactor [IGI, ISO]
- chaperone-mediated protein folding [ISO]
- clathrin coat disassembly [IGI]
- negative regulation of fibril organization [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- positive regulation of mRNA splicing, via spliceosome [IMP]
- protein folding [IDA]
- protein refolding [ISO]
- regulation of cell cycle [IDA]
Gene Ontology Molecular Function- ADP binding [ISO]
- ATP binding [ISO]
- ATPase activity [ISO]
- ATPase activity, coupled [IDA, ISO]
- G-protein coupled receptor binding [ISO]
- MHC class II protein complex binding [ISO]
- enzyme binding [ISO]
- heat shock protein binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- receptor binding [ISO]
- ubiquitin protein ligase binding [ISO]
- unfolded protein binding [IPI, ISO]
- ADP binding [ISO]
- ATP binding [ISO]
- ATPase activity [ISO]
- ATPase activity, coupled [IDA, ISO]
- G-protein coupled receptor binding [ISO]
- MHC class II protein complex binding [ISO]
- enzyme binding [ISO]
- heat shock protein binding [ISO]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- receptor binding [ISO]
- ubiquitin protein ligase binding [ISO]
- unfolded protein binding [IPI, ISO]
Gene Ontology Cellular Component
- Prp19 complex [ISO]
- blood microparticle [ISO]
- cytoplasm [ISO]
- cytosol [IDA, ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [IDA, ISO]
- focal adhesion [ISO]
- intracellular [IDA]
- membrane [ISO]
- myelin sheath [IDA]
- neuron projection [ISO]
- neuronal cell body [ISO]
- nucleus [ISO]
- protein complex [ISO]
- ribonucleoprotein complex [ISO]
- synaptic vesicle [ISO]
- terminal bouton [ISO]
- ubiquitin ligase complex [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.
In every synapse, a large number of proteins interact with other proteins in order to carry out signaling and transmission in the central nervous system. In this study, we used interaction proteomics to identify novel synaptic protein interactions in mouse cortical membranes under native conditions. Using immunoprecipitation, immunoblotting, and mass spectrometry, we identified a number of novel synaptic protein interactions ... [more]
FEBS Lett. Mar. 05, 2010; 584(5);845-51 [Pubmed: 20114047]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| KCNMA1 HSPA8 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID