KCNMA1
Gene Ontology Biological Process
- adult walking behavior [IMP]
- auditory receptor cell differentiation [IMP]
- cell maturation [IMP]
- cellular potassium ion homeostasis [ISO]
- circadian rhythm [IMP]
- eye blink reflex [IMP]
- locomotor rhythm [IMP]
- micturition [IMP, ISO]
- negative regulation of cell volume [IMP, ISO]
- neuromuscular process controlling balance [IMP]
- neuronal action potential [IMP]
- positive regulation of apoptotic process [ISO]
- potassium ion transmembrane transport [IBA, IGI, ISO]
- potassium ion transport [IDA, ISO]
- protein homooligomerization [IDA]
- protein homotetramerization [ISO]
- regulation of aldosterone metabolic process [IMP]
- regulation of ion transmembrane transport [IMP]
- regulation of membrane potential [IDA, IMP, ISO]
- regulation of vasodilation [ISO]
- relaxation of vascular smooth muscle [IMP]
- response to calcium ion [ISO]
- response to carbon monoxide [ISO]
- response to corticosteroid [ISO]
- response to estrogen [ISO]
- response to hypoxia [IDA, ISO]
- response to osmotic stress [ISO]
- response to pH [ISO]
- saliva secretion [IGI]
- sensory perception of sound [IMP]
- smooth muscle contraction involved in micturition [IMP, ISO]
- synaptic transmission [IMP]
- vasodilation [IMP]
Gene Ontology Molecular Function- actin binding [ISO]
- calcium-activated potassium channel activity [IDA, IGI, IMP, ISO]
- large conductance calcium-activated potassium channel activity [IDA, IMP, ISO]
- potassium channel activity [IGI, IMP]
- protein binding [IPI]
- protein complex binding [ISO]
- protein homodimerization activity [ISO]
- voltage-gated potassium channel activity [IDA, IMP, ISO]
- actin binding [ISO]
- calcium-activated potassium channel activity [IDA, IGI, IMP, ISO]
- large conductance calcium-activated potassium channel activity [IDA, IMP, ISO]
- potassium channel activity [IGI, IMP]
- protein binding [IPI]
- protein complex binding [ISO]
- protein homodimerization activity [ISO]
- voltage-gated potassium channel activity [IDA, IMP, ISO]
Gene Ontology Cellular Component
- apical plasma membrane [IDA, ISO]
- caveola [ISO]
- cell [IMP]
- cytoplasm [IDA]
- dendrite [ISO]
- endoplasmic reticulum [IDA]
- external side of plasma membrane [IDA, ISO]
- extracellular vesicular exosome [ISO]
- integral component of membrane [IC, IDA, ISO]
- neuronal cell body [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [IDA, ISO]
- postsynaptic membrane [IDA]
- presynaptic active zone membrane [ISO]
- protein complex [ISO]
- terminal bouton [IDA]
- voltage-gated potassium channel complex [IGI, ISO]
DNM1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.
In every synapse, a large number of proteins interact with other proteins in order to carry out signaling and transmission in the central nervous system. In this study, we used interaction proteomics to identify novel synaptic protein interactions in mouse cortical membranes under native conditions. Using immunoprecipitation, immunoblotting, and mass spectrometry, we identified a number of novel synaptic protein interactions ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| KCNMA1 DNM1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - | |
| DNM1 KCNMA1 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID