VAMP2
Gene Ontology Biological Process
- Golgi to plasma membrane protein transport [IMP]
- calcium ion-dependent exocytosis [IDA, IMP]
- cellular response to insulin stimulus [IDA]
- eosinophil degranulation [ISO]
- long-term synaptic potentiation [IMP]
- membrane fusion [IMP]
- positive regulation of intracellular protein transport [IMP]
- protein complex assembly [ISO]
- protein transport [ISO]
- regulation of exocytosis [IDA, ISO]
- regulation of vesicle-mediated transport [IMP]
- response to glucose [ISO]
- synaptic vesicle exocytosis [IMP]
- vesicle fusion [IBA]
- vesicle-mediated transport [ISO]
Gene Ontology Molecular Function- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
Gene Ontology Cellular Component
- SNARE complex [ISO]
- cell [IMP]
- clathrin-coated vesicle [ISO]
- cytoplasmic vesicle [IDA]
- extracellular vesicular exosome [ISO]
- intracellular [IMP]
- intracellular membrane-bounded organelle [ISO]
- intracellular organelle [ISO]
- membrane [ISO]
- neuron projection [ISO]
- neuron projection terminus [ISO]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA, ISO]
- secretory granule [IDA, ISO]
- synapse [IDA]
- synaptic vesicle [IDA, ISO]
- synaptic vesicle membrane [IDA]
- synaptobrevin 2-SNAP-25-syntaxin-1a complex [IDA, ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [ISO]
- terminal bouton [ISO]
- trans-Golgi network [IDA]
- zymogen granule membrane [IDA]
GNAO1
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IMP, ISO, TAS]
- GTP catabolic process [ISO]
- adenylate cyclase-modulating G-protein coupled receptor signaling pathway [IBA]
- aging [ISO]
- cellular process [IMP]
- dopamine receptor signaling pathway [IMP]
- locomotory behavior [IMP]
- negative regulation of calcium ion transport [ISO]
- positive regulation of GTPase activity [ISO]
- regulation of heart contraction [IMP]
- response to organonitrogen compound [ISO]
Gene Ontology Molecular Function- G-protein beta/gamma-subunit complex binding [IBA]
- G-protein coupled serotonin receptor binding [IBA, ISO]
- GTP binding [IMP, ISO]
- GTPase activating protein binding [ISO]
- GTPase activity [IDA, ISO, TAS]
- corticotropin-releasing hormone receptor 1 binding [IBA, ISO]
- mu-type opioid receptor binding [IBA, ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- signal transducer activity [IBA]
- G-protein beta/gamma-subunit complex binding [IBA]
- G-protein coupled serotonin receptor binding [IBA, ISO]
- GTP binding [IMP, ISO]
- GTPase activating protein binding [ISO]
- GTPase activity [IDA, ISO, TAS]
- corticotropin-releasing hormone receptor 1 binding [IBA, ISO]
- mu-type opioid receptor binding [IBA, ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- signal transducer activity [IBA]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.
In every synapse, a large number of proteins interact with other proteins in order to carry out signaling and transmission in the central nervous system. In this study, we used interaction proteomics to identify novel synaptic protein interactions in mouse cortical membranes under native conditions. Using immunoprecipitation, immunoblotting, and mass spectrometry, we identified a number of novel synaptic protein interactions ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| GNAO1 VAMP2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| GNAO1 VAMP2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID