BAIT
VAMP2
Syb-2, Syb2, sybII, RP23-26L6.8
vesicle-associated membrane protein 2
GO Process (15)
GO Function (12)
GO Component (23)
Gene Ontology Biological Process
- Golgi to plasma membrane protein transport [IMP]
- calcium ion-dependent exocytosis [IDA, IMP]
- cellular response to insulin stimulus [IDA]
- eosinophil degranulation [ISO]
- long-term synaptic potentiation [IMP]
- membrane fusion [IMP]
- positive regulation of intracellular protein transport [IMP]
- protein complex assembly [ISO]
- protein transport [ISO]
- regulation of exocytosis [IDA, ISO]
- regulation of vesicle-mediated transport [IMP]
- response to glucose [ISO]
- synaptic vesicle exocytosis [IMP]
- vesicle fusion [IBA]
- vesicle-mediated transport [ISO]
Gene Ontology Molecular Function- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
Gene Ontology Cellular Component
- SNARE complex [ISO]
- cell [IMP]
- clathrin-coated vesicle [ISO]
- cytoplasmic vesicle [IDA]
- extracellular vesicular exosome [ISO]
- intracellular [IMP]
- intracellular membrane-bounded organelle [ISO]
- intracellular organelle [ISO]
- membrane [ISO]
- neuron projection [ISO]
- neuron projection terminus [ISO]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA, ISO]
- secretory granule [IDA, ISO]
- synapse [IDA]
- synaptic vesicle [IDA, ISO]
- synaptic vesicle membrane [IDA]
- synaptobrevin 2-SNAP-25-syntaxin-1a complex [IDA, ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [ISO]
- terminal bouton [ISO]
- trans-Golgi network [IDA]
- zymogen granule membrane [IDA]
Mus musculus
PREY
ATP1A2
AW060654, Atpa-3, mKIAA0778
ATPase, Na+/K+ transporting, alpha 2 polypeptide
GO Process (30)
GO Function (6)
GO Component (15)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- ATP hydrolysis coupled proton transport [ISO]
- adult locomotory behavior [IMP]
- cellular potassium ion homeostasis [ISO]
- cellular response to mechanical stimulus [ISO]
- cellular response to steroid hormone stimulus [IDA, ISO]
- cellular sodium ion homeostasis [ISO]
- locomotion [IMP]
- negative regulation of calcium ion transmembrane transport [ISO]
- negative regulation of calcium:sodium antiporter activity [ISO]
- negative regulation of cytosolic calcium ion concentration [IMP]
- negative regulation of heart contraction [IMP]
- negative regulation of striated muscle contraction [IMP]
- neurotransmitter uptake [IMP]
- potassium ion import [ISO]
- potassium ion transport [ISO]
- regulation of blood pressure [IGI]
- regulation of cardiac muscle cell contraction [ISO]
- regulation of muscle contraction [IMP]
- regulation of respiratory gaseous exchange by neurological system process [IMP]
- regulation of smooth muscle contraction [IMP]
- regulation of striated muscle contraction [IMP]
- regulation of the force of heart contraction [IMP]
- regulation of vasoconstriction [IGI, IMP]
- response to glycoside [IMP, ISO]
- response to nicotine [ISO]
- sodium ion export from cell [ISO]
- sodium ion transmembrane transport [ISO]
- sodium ion transport [ISO]
- visual learning [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.
In every synapse, a large number of proteins interact with other proteins in order to carry out signaling and transmission in the central nervous system. In this study, we used interaction proteomics to identify novel synaptic protein interactions in mouse cortical membranes under native conditions. Using immunoprecipitation, immunoblotting, and mass spectrometry, we identified a number of novel synaptic protein interactions ... [more]
FEBS Lett. Mar. 05, 2010; 584(5);845-51 [Pubmed: 20114047]
Throughput
- Low Throughput
Curated By
- BioGRID