BAIT
VAMP2
Syb-2, Syb2, sybII, RP23-26L6.8
vesicle-associated membrane protein 2
GO Process (15)
GO Function (12)
GO Component (23)
Gene Ontology Biological Process
- Golgi to plasma membrane protein transport [IMP]
- calcium ion-dependent exocytosis [IDA, IMP]
- cellular response to insulin stimulus [IDA]
- eosinophil degranulation [ISO]
- long-term synaptic potentiation [IMP]
- membrane fusion [IMP]
- positive regulation of intracellular protein transport [IMP]
- protein complex assembly [ISO]
- protein transport [ISO]
- regulation of exocytosis [IDA, ISO]
- regulation of vesicle-mediated transport [IMP]
- response to glucose [ISO]
- synaptic vesicle exocytosis [IMP]
- vesicle fusion [IBA]
- vesicle-mediated transport [ISO]
Gene Ontology Molecular Function- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
- SNAP receptor activity [IBA]
- SNARE binding [IDA, ISO]
- calcium-dependent protein binding [ISO]
- calmodulin binding [IDA]
- identical protein binding [ISO]
- myosin binding [ISO]
- phospholipid binding [IDA]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- syntaxin binding [IPI, ISO]
- syntaxin-1 binding [ISO]
Gene Ontology Cellular Component
- SNARE complex [ISO]
- cell [IMP]
- clathrin-coated vesicle [ISO]
- cytoplasmic vesicle [IDA]
- extracellular vesicular exosome [ISO]
- intracellular [IMP]
- intracellular membrane-bounded organelle [ISO]
- intracellular organelle [ISO]
- membrane [ISO]
- neuron projection [ISO]
- neuron projection terminus [ISO]
- perinuclear region of cytoplasm [IDA]
- plasma membrane [IDA, ISO]
- secretory granule [IDA, ISO]
- synapse [IDA]
- synaptic vesicle [IDA, ISO]
- synaptic vesicle membrane [IDA]
- synaptobrevin 2-SNAP-25-syntaxin-1a complex [IDA, ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex [ISO]
- synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex [ISO]
- terminal bouton [ISO]
- trans-Golgi network [IDA]
- zymogen granule membrane [IDA]
Mus musculus
PREY
ATP1A1
Atpa-1, BC010319
ATPase, Na+/K+ transporting, alpha 1 polypeptide
GO Process (24)
GO Function (13)
GO Component (18)
Gene Ontology Biological Process
- ATP catabolic process [IMP]
- cellular potassium ion homeostasis [ISO]
- cellular response to mechanical stimulus [ISO]
- cellular response to steroid hormone stimulus [ISO]
- cellular sodium ion homeostasis [ISO]
- dephosphorylation [IMP]
- membrane hyperpolarization [ISO]
- membrane repolarization [ISO]
- negative regulation of glucocorticoid biosynthetic process [IMP]
- negative regulation of heart contraction [IMP]
- positive regulation of heart contraction [IMP]
- positive regulation of striated muscle contraction [IMP]
- potassium ion import [ISO]
- potassium ion transmembrane transport [IMP]
- potassium ion transport [ISO]
- regulation of blood pressure [IGI]
- regulation of cardiac muscle cell contraction [ISO]
- regulation of sodium ion transport [ISO]
- regulation of the force of heart contraction [IMP]
- response to drug [IMP]
- response to glycoside [IGI]
- sodium ion export from cell [ISO]
- sodium ion transmembrane transport [IMP, ISO]
- sodium ion transport [ISO]
Gene Ontology Molecular Function- ADP binding [ISO]
- ATP binding [ISO]
- ankyrin binding [ISO]
- chaperone binding [ISO]
- phosphatase activity [IMP]
- phosphatidylinositol 3-kinase binding [ISO]
- potassium ion binding [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein kinase binding [ISO]
- sodium ion binding [ISO]
- sodium:potassium-exchanging ATPase activity [IDA, IMP, ISO]
- steroid hormone binding [ISO]
- ADP binding [ISO]
- ATP binding [ISO]
- ankyrin binding [ISO]
- chaperone binding [ISO]
- phosphatase activity [IMP]
- phosphatidylinositol 3-kinase binding [ISO]
- potassium ion binding [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein kinase binding [ISO]
- sodium ion binding [ISO]
- sodium:potassium-exchanging ATPase activity [IDA, IMP, ISO]
- steroid hormone binding [ISO]
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- T-tubule [IDA, ISO]
- apical plasma membrane [IDA]
- basolateral plasma membrane [IDA]
- caveola [ISO]
- endoplasmic reticulum [ISO]
- endosome [ISO]
- extracellular vesicular exosome [ISO]
- intercalated disc [ISO]
- membrane [IDA, ISO]
- membrane raft [ISO]
- myelin sheath [IDA]
- neuronal postsynaptic density [IDA]
- plasma membrane [IDA, ISO]
- protein complex [ISO]
- sarcolemma [IDA, ISO]
- sodium:potassium-exchanging ATPase complex [ISO]
- vesicle [ISO]
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.
In every synapse, a large number of proteins interact with other proteins in order to carry out signaling and transmission in the central nervous system. In this study, we used interaction proteomics to identify novel synaptic protein interactions in mouse cortical membranes under native conditions. Using immunoprecipitation, immunoblotting, and mass spectrometry, we identified a number of novel synaptic protein interactions ... [more]
FEBS Lett. Mar. 05, 2010; 584(5);845-51 [Pubmed: 20114047]
Throughput
- Low Throughput
Curated By
- BioGRID