BAIT
EED
ENSMUSG00000039373, l(7)5Rn, l7Rn5, lusk
embryonic ectoderm development
GO Process (4)
GO Function (4)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
AP3D1
AA407035, Ap3d, Bolvr, mBLVR1, mh, mocha
adaptor-related protein complex 3, delta 1 subunit
GO Process (13)
GO Function (0)
GO Component (9)
Gene Ontology Biological Process
- anterograde axon cargo transport [IMP]
- anterograde synaptic vesicle transport [IMP]
- antigen processing and presentation [IMP]
- antigen processing and presentation, exogenous lipid antigen via MHC class Ib [IMP]
- endosome to melanosome transport [ISO]
- intracellular protein transport [IMP, TAS]
- positive regulation of NK T cell differentiation [IMP]
- protein localization to membrane [ISO]
- protein localization to organelle [IMP]
- regulation of sequestering of zinc ion [ISO, TAS]
- synaptic vesicle membrane organization [IMP]
- vesicle-mediated transport [TAS]
- zinc ion transport [TAS]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The central role of EED in the orchestration of polycomb group complexes.
Polycomb repressive complexes 1 and 2 (PRC1 and 2) play a critical role in the epigenetic regulation of transcription during cellular differentiation, stem cell pluripotency and neoplastic progression. Here we show that the polycomb group protein EED, a core component of PRC2, physically interacts with and functions as part of PRC1. Components of PRC1 and PRC2 compete for EED binding. ... [more]
Nat Commun Jan. 24, 2014; 5(0);3127 [Pubmed: 24457600]
Throughput
- High Throughput
Curated By
- BioGRID