BAIT
GGA2
VEAR
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GO Process (1)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TOLLIP
IL-1RAcPIP
toll interacting protein
GO Process (8)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Tollip and Tom1 form a complex and recruit ubiquitin-conjugated proteins onto early endosomes.
Tom1 (target of Myb1) is a protein of unknown function. Tom1 and its relative Tom1L1 have an N-terminal VHS (Vps27p/Hrs/Stam) domain followed by a GAT (GGA and Tom1) domain, both of which are also found in the GGA (Golgi-localizing, gamma-adaptin ear domain homology, ADP-ribosylation factor-binding protein) family of proteins. Although the VHS and GAT domains of GGA proteins bind to ... [more]
J. Biol. Chem. Jun. 04, 2004; 279(23);24435-43 [Pubmed: 15047686]
Throughput
- Low Throughput
Additional Notes
- Figure 3A
Curated By
- BioGRID