NEURL1A
Gene Ontology Biological Process
- cellular response to amino acid stimulus [IDA]
- lactation [IMP]
- negative regulation of Notch signaling pathway [ISO]
- negative regulation of cell proliferation [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of dendritic spine development [IDA]
- positive regulation of epidermal growth factor-activated receptor activity [IMP]
- positive regulation of filopodium assembly [IDA]
- positive regulation of long-term neuronal synaptic plasticity [IDA]
- positive regulation of synapse maturation [IDA]
- protein monoubiquitination [IDA]
- regulation of translation [IDA]
- sperm axoneme assembly [IMP]
- sperm motility [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
NEURL1A
Gene Ontology Biological Process
- cellular response to amino acid stimulus [IDA]
- lactation [IMP]
- negative regulation of Notch signaling pathway [ISO]
- negative regulation of cell proliferation [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of dendritic spine development [IDA]
- positive regulation of epidermal growth factor-activated receptor activity [IMP]
- positive regulation of filopodium assembly [IDA]
- positive regulation of long-term neuronal synaptic plasticity [IDA]
- positive regulation of synapse maturation [IDA]
- protein monoubiquitination [IDA]
- regulation of translation [IDA]
- sperm axoneme assembly [IMP]
- sperm motility [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Biochemical Activity (Ubiquitination)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1.
Mutations in Drosophila neuralized (Dneur) result in a variety of developmental defects that closely resemble those of Notch mutants and other Notch pathway mutants. However, mice with disrupted neur1 do not show any aberrant cell fate specifications in neurogenesis and somitogenesis. Thus, we speculated that other vertebrate neur homolog(s) might compensate for loss of the neur gene. Here, we report ... [more]
Throughput
- Low Throughput
Additional Notes
- E2: UbcH5a
- self-ubiquitination
Curated By
- BioGRID