BAIT
UBC
2700054O04Rik, AI194771, Rps27a, TI-225, Uba52, Ubb
ubiquitin C
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
REV1
1110027I23Rik, AU022044, Rev1l
REV1 homolog (S. cerevisiae)
GO Process (2)
GO Function (1)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Ubiquitin-binding motifs in REV1 protein are required for its role in the tolerance of DNA damage.
REV1 protein is a eukaryotic member of the Y family of DNA polymerases involved in the tolerance of DNA damage by replicative bypass. The precise role(s) of REV1 in this process is not known. Here we show, by using the yeast two-hybrid assay and the glutathione S-transferase pull-down assay, that mouse REV1 can physically interact with ubiquitin. The association of ... [more]
Mol. Cell. Biol. Dec. 01, 2006; 26(23);8892-900 [Pubmed: 16982685]
Throughput
- Low Throughput
Additional Notes
- #LPPI
- Figure 1
- Likely protein-protein interaction
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
REV1 UBC | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | 1107253 |
Curated By
- BioGRID