BAIT

LUZP4

CT-28, CT-8, CT28, HOM-TES-85, RP1-237H22.1
leucine zipper protein 4
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

FUS

ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS
FUS RNA binding protein
GO Process (3)
GO Function (4)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Luzp4 defines a new mRNA export pathway in cancer cells.

Viphakone N, Cumberbatch MG, Livingstone MJ, Heath PR, Dickman MJ, Catto JW, Wilson SA

Cancer testis antigens (CTAs) represented a poorly characterized group of proteins whose expression is normally restricted to testis but are frequently up-regulated in cancer cells. Here we show that one CTA, Luzp4, is an mRNA export adaptor. It associates with the TREX mRNA export complex subunit Uap56 and harbours a Uap56 binding motif, conserved in other mRNA export adaptors. Luzp4 ... [more]

Nucleic Acids Res. Feb. 27, 2015; 43(4);2353-66 [Pubmed: 25662211]

Throughput

  • High Throughput

Curated By

  • BioGRID