BAIT
HSP81-2
AtHsp90.2, EARLY-RESPONSIVE TO DEHYDRATION 8, ERD8, HEAT SHOCK PROTEIN 81-2, HEAT SHOCK PROTEIN 90.2, HSP90.2, MDA7.7, MDA7_7, AT5G56030
heat shock protein 81-2
GO Process (13)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- chaperone-mediated protein complex assembly [IMP]
- defense response [IMP]
- defense response to bacterium, incompatible interaction [IMP]
- flower development [IMP]
- heat acclimation [IEP]
- leaf development [IMP]
- negative regulation of seed germination [IMP]
- protein folding [ISS]
- protein stabilization [IMP]
- response to heat [IEP]
- response to salt stress [IMP]
- response to water deprivation [IMP]
- stomatal closure [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Arabidopsis thaliana (Columbia)
PREY
SGT1B
ATSGT1B, EDM1, ENHANCED DOWNY MILDEW 1, ENHANCER OF TIR1-1 AUXIN RESISTANCE 3, ETA3, F8L21.50, F8L21_50, RPR1, AT4G11260
phosphatase SGT1b
GO Process (8)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- auxin-activated signaling pathway [IMP]
- defense response to fungus [IMP]
- jasmonic acid mediated signaling pathway [IMP]
- negative regulation of seed germination [IMP]
- protein catabolic process [IMP]
- regulation of defense response to fungus, incompatible interaction [IMP]
- response to heat [IMP]
- ubiquitin-dependent protein catabolic process [IMP]
Gene Ontology Molecular Function
Arabidopsis thaliana (Columbia)
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Specific Arabidopsis HSP90.2 alleles recapitulate RAR1 cochaperone function in plant NB-LRR disease resistance protein regulation.
Both plants and animals require the activity of proteins containing nucleotide binding (NB) domain and leucine-rich repeat (LRR) domains for proper immune system function. NB-LRR proteins in plants (NLR proteins in animals) also require conserved regulation via the proteins SGT1 and cytosolic HSP90. RAR1, a protein specifically required for plant innate immunity, interacts with SGT1 and HSP90 to maintain proper ... [more]
Proc. Natl. Acad. Sci. U.S.A. Jun. 16, 2009; 106(24);9556-63 [Pubmed: 19487680]
Throughput
- Low Throughput
Curated By
- BioGRID