BAIT
ESRP1
2210008M09Rik, A630065D16, BC031468, Rbm35a, RP23-322G9.1
epithelial splicing regulatory protein 1
GO Process (1)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
MYC
AU016757, Myc2, Niard, Nird, bHLHe39
myelocytomatosis oncogene
GO Process (67)
GO Function (13)
GO Component (11)
Gene Ontology Biological Process
- B cell apoptotic process [IMP]
- DNA-templated transcription, initiation [ISO]
- MAPK cascade [ISO]
- Wnt signaling pathway [IDA]
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- amino acid transport [ISO]
- branching involved in ureteric bud morphogenesis [IMP]
- canonical Wnt signaling pathway [ISO]
- canonical Wnt signaling pathway involved in negative regulation of apoptotic process [IGI]
- canonical Wnt signaling pathway involved in positive regulation of apoptotic process [IGI]
- canonical Wnt signaling pathway involved in positive regulation of wound healing [ISO]
- cell cycle arrest [ISO]
- cell proliferation [ISO]
- cellular iron ion homeostasis [ISO]
- cellular response to DNA damage stimulus [IDA, ISO]
- cellular response to drug [IDA, ISO]
- chromatin remodeling [ISO]
- chromosome organization [ISO]
- detection of mechanical stimulus involved in sensory perception of sound [IMP]
- glucose metabolic process [ISO]
- inner mitochondrial membrane organization [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage [IDA, IMP]
- lactic acid secretion [ISO]
- middle ear morphogenesis [IMP]
- negative regulation of cell death [ISO]
- negative regulation of cell division [ISO]
- negative regulation of fibroblast proliferation [ISO]
- negative regulation of gene expression [ISO]
- negative regulation of glucose import [ISO]
- negative regulation of monocyte differentiation [ISO]
- negative regulation of protein binding [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- pigmentation [IMP]
- positive regulation of ATP biosynthetic process [ISO]
- positive regulation of B cell apoptotic process [IGI]
- positive regulation of DNA biosynthetic process [ISO]
- positive regulation of apoptotic signaling pathway [IDA, IMP]
- positive regulation of catalytic activity [IMP]
- positive regulation of cell cycle [ISO]
- positive regulation of cell proliferation [IDA, IGI, ISO]
- positive regulation of cellular respiration [ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of epithelial cell proliferation [ISO]
- positive regulation of fibroblast proliferation [ISO]
- positive regulation of glycolytic process [ISO]
- positive regulation of mesenchymal cell proliferation [IMP]
- positive regulation of metanephric cap mesenchymal cell proliferation [IMP]
- positive regulation of mitochondrial membrane potential [ISO]
- positive regulation of response to DNA damage stimulus [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- protein processing [IMP]
- pyruvate transport [ISO]
- regulation of apoptotic process [IDA, IMP]
- regulation of gene expression [IDA, ISO]
- regulation of mitotic cell cycle [ISO]
- regulation of oxidative phosphorylation [ISO]
- regulation of telomere maintenance [ISO]
- regulation of transcription, DNA-templated [IGI, ISO]
- response to alkaloid [IMP]
- response to gamma radiation [ISO]
- response to radiation [IDA, IMP]
- skeletal muscle cell differentiation [IMP]
- skeletal system morphogenesis [IMP]
- transcription from RNA polymerase II promoter [ISO]
- transcription, DNA-templated [ISO]
- transformation of host cell by virus [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- E-box binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- core promoter proximal region sequence-specific DNA binding [IDA]
- double-stranded DNA binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein heterodimerization activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [ISO]
- DNA binding [IDA, ISO]
- E-box binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- core promoter proximal region sequence-specific DNA binding [IDA]
- double-stranded DNA binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein heterodimerization activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription factor binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells.
In pluripotent stem cells, there is increasing evidence for crosstalk between post-transcriptional and transcriptional networks, offering multifold steps at which pluripotency can be controlled. In addition to well-studied transcription factors, chromatin modifiers and miRNAs, RNA-binding proteins are emerging as fundamental players in pluripotency regulation. Here, we report a new role for the RNA-binding protein ESRP1 in the control of pluripotency. ... [more]
PLoS ONE Sep. 10, 2013; 8(8);e72300 [Pubmed: 24015231]
Throughput
- Low Throughput
Curated By
- BioGRID