BAIT
HEN1
CORYMBOSA 2, CRM2, HUA ENHANCER 1, T13K14.70, T13K14_70, AT4G20910
small RNA 2'-O-methyltransferase
GO Process (8)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- leaf proximal/distal pattern formation [IMP]
- leaf vascular tissue pattern formation [IMP]
- mRNA cleavage involved in gene silencing by miRNA [IMP]
- production of miRNAs involved in gene silencing by miRNA [IMP, NAS]
- production of siRNA involved in RNA interference [IGI, IMP]
- regulation of flower development [IMP]
- specification of floral organ identity [IMP]
- virus induced gene silencing [IMP]
Gene Ontology Molecular Function
Arabidopsis thaliana (Columbia)
PREY
MIR173
microRNA173, AT3G23125
ncRNA
GO Process (1)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Arabidopsis thaliana (Columbia)
Protein-RNA
An interaction is detected between and protein and an RNA in vitro.
Publication
Functional mapping of the plant small RNA methyltransferase: HEN1 physically interacts with HYL1 and DICER-LIKE 1 proteins.
Methylation of 3'-terminal nucleotides of miRNA/miRNA* is part of miRNAs biogenesis in plants but is not found in animals. In Arabidopsis thaliana this reaction is carried out by a multidomain AdoMet-dependent 2'-O-methyltransferase HEN1. Using deletion and structure-guided mutational analysis, we show that the double-stranded RNA-binding domains R(1) and R(2) of HEN1 make significant but uneven contributions to substrate RNA binding, ... [more]
Nucleic Acids Res. Mar. 11, 2015; 43(5);2802-12 [Pubmed: 25680966]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HEN1 MIR173 | Protein-RNA Protein-RNA An interaction is detected between and protein and an RNA in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID