BAIT
HYL1
DRB1, DSRNA-BINDING PROTEIN 1, F21M12.9, F21M12_9, HYPONASTIC LEAVES 1, AT1G09700
double-stranded RNA-binding protein 1
GO Process (9)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- leaf proximal/distal pattern formation [IMP]
- leaf vascular tissue pattern formation [IMP]
- mRNA cleavage involved in gene silencing by miRNA [IMP]
- pre-miRNA processing [IMP]
- production of miRNAs involved in gene silencing by miRNA [IMP]
- production of ta-siRNAs involved in RNA interference [IMP]
- response to abscisic acid [IMP]
- response to auxin [IMP]
- response to cytokinin [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Arabidopsis thaliana (Columbia)
PREY
HON4
HISTONE H1, AT3G18035
protein HON4
GO Process (1)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- nucleosome [ISS]
- nucleus [ISM]
Arabidopsis thaliana (Columbia)
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Homodimerization of HYL1 ensures the correct selection of cleavage sites in primary miRNA.
MicroRNA (miRNA) plays an important role in the control of gene expression. HYPONASTIC LEAVES1 (HYL1) is a double-stranded RNA-binding protein that forms a complex with DICER-LIKE1 (DCL1) and SERRATE (SE) to process primary miRNA (pri-miRNA) into mature miRNA. Although HYL1 has been shown to partner with DCL1 to enhance miRNA accuracy, the mechanism by which HYL1 selects the DCL1-targeted cleavage ... [more]
Nucleic Acids Res. Oct. 29, 2014; 42(19);12224-36 [Pubmed: 25294831]
Throughput
- Low Throughput
Curated By
- BioGRID