BAIT

ABCE1

ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I, OK/SW-cl.40

ATP-binding cassette, sub-family E (OABP), member 1

Autism spectrum disorder (ASD) Project

GO Process (3)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

RNA catabolic process [TAS]

negative regulation of catalytic activity [TAS]

response to virus [TAS]

Gene Ontology Molecular Function

ribonuclease inhibitor activity [TAS]

Gene Ontology Cellular Component

cytoplasm [IDA]

mitochondrion [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

TFAM

MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3

transcription factor A, mitochondrial

GO Process (8)

GO Function (8)

GO Component (4)

Gene Ontology Biological Process

DNA-dependent DNA replication [TAS]

chromatin remodeling [IBA]

gene expression [TAS]

positive regulation of transcription from RNA polymerase II promoter [IDA]

positive regulation of transcription, DNA-templated [IDA]

regulation of transcription from RNA polymerase I promoter [TAS]

transcription from mitochondrial promoter [IMP, TAS]

transcription initiation from mitochondrial promoter [IDA, TAS]

Gene Ontology Molecular Function

DNA binding, bending [IDA]
RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IC]
chromatin binding [IDA]
mitochondrial light strand promoter sense binding [IDA]
poly(A) RNA binding [IDA]
protein binding [IPI]
sequence-specific DNA binding transcription factor activity [IMP]

Gene Ontology Cellular Component

mitochondrial matrix [TAS]

mitochondrial nucleoid [IDA]

mitochondrion [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

ABCE1 is a highly conserved RNA silencing suppressor.

Kaerblane K, Gerassimenko J, Nigul L, Piirsoo A, Smialowska A, Vinkel K, Kylsten P, Ekwall K, Swoboda P, Truve E, Sarmiento C

ATP-binding cassette sub-family E member 1 (ABCE1) is a highly conserved protein among eukaryotes and archaea. Recent studies have identified ABCE1 as a ribosome-recycling factor important for translation termination in mammalian cells, yeast and also archaea. Here we report another conserved function of ABCE1. We have previously described AtRLI2, the homolog of ABCE1 in the plant Arabidopsis thaliana, as an ... [more]

PLoS ONE Feb. 07, 2015; 10(2);e0116702 [Pubmed: 25659154]

Throughput

Low Throughput

Curated By

BioGRID