BAIT

ABCE1

ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I, OK/SW-cl.40

ATP-binding cassette, sub-family E (OABP), member 1

Autism spectrum disorder (ASD) Project

GO Process (3)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

RNA catabolic process [TAS]

negative regulation of catalytic activity [TAS]

response to virus [TAS]

Gene Ontology Molecular Function

ribonuclease inhibitor activity [TAS]

Gene Ontology Cellular Component

cytoplasm [IDA]

mitochondrion [IDA]

CRISPR Database HGNC Alliance of Genome Resources OMIM VEGA Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

AIFM1

AIF, CMT2D, CMTX4, COWCK, COXPD6, NADMR, NAMSD, PDCD8, RP3-438D16.2

apoptosis-inducing factor, mitochondrion-associated, 1

GO Process (9)

GO Function (4)

GO Component (5)

Gene Ontology Biological Process

DNA catabolic process [TAS]

activation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]

apoptotic DNA fragmentation [TAS]

apoptotic process [IMP]

chromosome condensation [TAS]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [ISS]

mitochondrial respiratory chain complex I assembly [IMP]

neuron differentiation [IDA]

positive regulation of apoptotic process [TAS]

Gene Ontology Molecular Function

NAD(P)H oxidase activity [TAS]
electron carrier activity [TAS]
oxidoreductase activity, acting on NAD(P)H [IDA]
protein binding [IPI]

Gene Ontology Cellular Component

mitochondrial inner membrane [TAS]

mitochondrial intermembrane space [IDA, IMP]

mitochondrion [IDA]

nucleus [IDA, ISS]

CRISPR Database OMIM VEGA HGNC Alliance of Genome Resources OMIM Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

ABCE1 is a highly conserved RNA silencing suppressor.

Kaerblane K, Gerassimenko J, Nigul L, Piirsoo A, Smialowska A, Vinkel K, Kylsten P, Ekwall K, Swoboda P, Truve E, Sarmiento C

ATP-binding cassette sub-family E member 1 (ABCE1) is a highly conserved protein among eukaryotes and archaea. Recent studies have identified ABCE1 as a ribosome-recycling factor important for translation termination in mammalian cells, yeast and also archaea. Here we report another conserved function of ABCE1. We have previously described AtRLI2, the homolog of ABCE1 in the plant Arabidopsis thaliana, as an ... [more]

PLoS ONE Feb. 07, 2015; 10(2);e0116702 [Pubmed: 25659154]

Throughput

Low Throughput

Curated By

BioGRID