MSN2
Gene Ontology Biological Process
- age-dependent response to oxidative stress involved in chronological cell aging [IGI]
- cellular response to blue light [IDA]
- cellular response to methylmercury [IGI, IMP]
- chromatin remodeling [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [IGI, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to cold [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to ethanol [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to freezing [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to heat stress [IGI, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide [IGI, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to increased salt [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [IGI]
- regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction [IGI]
- replicative cell aging [IGI]
Gene Ontology Molecular Function
MSN4
Gene Ontology Biological Process
- age-dependent response to oxidative stress involved in chronological cell aging [IGI]
- cellular response to acidic pH [IMP]
- chromatin remodeling [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to acidic pH [IGI, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to cold [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to ethanol [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to freezing [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to heat stress [IGI, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide [IGI, IMP]
- positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to increased salt [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress [IGI]
- positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation [IGI]
- regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction [IGI]
- replicative cell aging [IGI]
Gene Ontology Molecular Function
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
A Genetic Screen for Saccharomyces cerevisiae Mutants that Fail to Enter Quiescence.
Budding yeast begin the transition to quiescence by prolonging G1 and accumulating limited nutrients. They undergo asymmetric cell divisions, slow cellular expansion, acquire significant stress tolerance and construct elaborate cell walls. These morphological changes give rise to quiescent (Q) cells, which can be distinguished from three other cell types in a stationary phase culture by flow cytometry. We have used ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: metabolism and growth (APO:0000094)
Additional Notes
- double mutants show a loss of R3 cells and excess G2 cells compared to wildtype and single mutants
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| MSN2 MSN4 | Dosage Rescue Dosage Rescue A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene. | Low | - | BioGRID | 154843 | |
| MSN2 MSN4 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -4.469 | BioGRID | 542202 | |
| MSN4 MSN2 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 519023 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 156438 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 2660023 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 156441 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 156434 | |
| MSN4 MSN2 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 163997 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 156435 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 156439 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 2393765 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 858915 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 2339809 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 2529223 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 156440 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 256334 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 156437 | |
| MSN4 MSN2 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 559775 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 156433 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 481910 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 795880 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 2450313 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 162103 | |
| MSN2 MSN4 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 2400151 | |
| MSN2 MSN4 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 564295 | |
| MSN2 MSN4 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 463369 | |
| MSN2 MSN4 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 256327 | |
| MSN2 MSN4 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 1521950 | |
| MSN2 MSN4 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 3394653 | |
| MSN2 MSN4 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 2347851 | |
| MSN2 MSN4 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 2394269 | |
| MSN2 MSN4 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 449972 | |
| MSN2 MSN4 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 349123 | |
| MSN4 MSN2 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 559740 |
Curated By
- BioGRID