BAIT

ILF2

NF45, PRO3063, RP11-354A16.1
interleukin enhancer binding factor 2
GO Process (2)
GO Function (4)
GO Component (5)
Homo sapiens
PREY

SHMT2

GLYA, HEL-S-51e, SHMT
serine hydroxymethyltransferase 2 (mitochondrial)
GO Process (1)
GO Function (2)
GO Component (6)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus.

Karmakar S, Mahajan MC, Schulz V, Boyapaty G, Weissman SM

DNA replication, repair, transcription and chromatin structure are intricately associated nuclear processes, but the molecular links between these events are often obscure. In this study, we have surveyed the protein complexes that bind at β-globin locus control region, and purified and characterized the function of one such multiprotein complex from human erythroleukemic K562 cells. We further validated the existence of ... [more]

EMBO J. Oct. 06, 2010; 29(19);3260-71 [Pubmed: 20808282]

Throughput

  • High Throughput

Curated By

  • BioGRID