BAIT
CSNK1E
CKIepsilon, HCKIE, RP1-5O6.1
casein kinase 1, epsilon
GO Process (12)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- DNA repair [TAS]
- G2/M transition of mitotic cell cycle [TAS]
- Wnt signaling pathway [IBA]
- circadian regulation of gene expression [ISS]
- endocytosis [IBA]
- mitotic cell cycle [TAS]
- peptidyl-serine phosphorylation [IBA]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- protein phosphorylation [IDA, ISS]
- regulation of cell shape [IBA]
- regulation of circadian rhythm [ISS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
DEC1
CTS9
deleted in esophageal cancer 1
GO Process (1)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.
Essentially all biological processes depend on protein-protein interactions (PPIs). Timing of such interactions is crucial for regulatory function. Although circadian (~24-hour) clocks constitute fundamental cellular timing mechanisms regulating important physiological processes, PPI dynamics on this timescale are largely unknown. Here, we identified 109 novel PPIs among circadian clock proteins via a yeast-two-hybrid approach. Among them, the interaction of protein phosphatase ... [more]
PLoS Genet. Mar. 01, 2013; 9(3);e1003398 [Pubmed: 23555304]
Throughput
- Low Throughput
Curated By
- BioGRID