CSNK1D
Gene Ontology Biological Process
- DNA repair [TAS]
- G2/M transition of mitotic cell cycle [TAS]
- circadian regulation of gene expression [ISS]
- endocytosis [IBA]
- mitotic cell cycle [TAS]
- peptidyl-serine phosphorylation [IBA]
- positive regulation of canonical Wnt signaling pathway [IMP]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- positive regulation of protein phosphorylation [IMP]
- protein phosphorylation [IDA]
- regulation of cell shape [IBA]
- regulation of circadian rhythm [ISS]
- signal transduction [TAS]
- spindle assembly [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PER2
Gene Ontology Biological Process
- circadian regulation of gene expression [ISS]
- circadian regulation of translation [ISS]
- circadian rhythm [TAS]
- fatty acid metabolic process [ISS]
- gluconeogenesis [ISS]
- glycogen biosynthetic process [ISS]
- histone H3 deacetylation [ISS]
- lactate biosynthetic process [ISS]
- negative regulation of circadian rhythm [ISS]
- negative regulation of fat cell proliferation [ISS]
- negative regulation of protein ubiquitination [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- negative regulation of transcription regulatory region DNA binding [ISS]
- negative regulation of transcription, DNA-templated [ISS]
- regulation of cell cycle [ISS]
- regulation of circadian rhythm [ISS]
- regulation of glutamate uptake involved in transmission of nerve impulse [ISS]
- regulation of insulin secretion [ISS]
- regulation of neurogenesis [ISS]
- regulation of vasoconstriction [ISS]
- response to ischemia [ISS]
- white fat cell differentiation [ISS]
Gene Ontology Molecular Function
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.
Essentially all biological processes depend on protein-protein interactions (PPIs). Timing of such interactions is crucial for regulatory function. Although circadian (~24-hour) clocks constitute fundamental cellular timing mechanisms regulating important physiological processes, PPI dynamics on this timescale are largely unknown. Here, we identified 109 novel PPIs among circadian clock proteins via a yeast-two-hybrid approach. Among them, the interaction of protein phosphatase ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CSNK1D PER2 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9999 | BioGRID | 3116258 | |
| PER2 CSNK1D | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | 2723319 |
Curated By
- BioGRID