ARNTL
Gene Ontology Biological Process
- circadian regulation of gene expression [IDA, ISS]
- circadian rhythm [TAS]
- negative regulation of TOR signaling [ISS]
- negative regulation of fat cell differentiation [ISS]
- negative regulation of glucocorticoid receptor signaling pathway [ISS]
- negative regulation of transcription, DNA-templated [ISS]
- oxidative stress-induced premature senescence [ISS]
- positive regulation of canonical Wnt signaling pathway [ISS]
- positive regulation of circadian rhythm [ISS]
- positive regulation of skeletal muscle cell differentiation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- positive regulation of transcription, DNA-templated [IDA, IMP]
- proteasome-mediated ubiquitin-dependent protein catabolic process [ISS]
- regulation of cell cycle [ISS]
- regulation of cellular senescence [ISS]
- regulation of hair cycle [IMP]
- regulation of insulin secretion [ISS]
- regulation of neurogenesis [ISS]
- regulation of transcription, DNA-templated [ISS]
- regulation of type B pancreatic cell development [ISS]
- response to redox state [IDA]
- spermatogenesis [ISS]
Gene Ontology Molecular Function- DNA binding [IDA, IGI]
- E-box binding [IDA]
- Hsp90 protein binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity [ISS]
- aryl hydrocarbon receptor binding [IPI]
- core promoter binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding [ISS]
- transcription regulatory region sequence-specific DNA binding [ISS]
- DNA binding [IDA, IGI]
- E-box binding [IDA]
- Hsp90 protein binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity [ISS]
- aryl hydrocarbon receptor binding [IPI]
- core promoter binding [ISS]
- protein binding [IPI]
- sequence-specific DNA binding [ISS]
- transcription regulatory region sequence-specific DNA binding [ISS]
Gene Ontology Cellular Component
CSNK1E
Gene Ontology Biological Process
- DNA repair [TAS]
- G2/M transition of mitotic cell cycle [TAS]
- Wnt signaling pathway [IBA]
- circadian regulation of gene expression [ISS]
- endocytosis [IBA]
- mitotic cell cycle [TAS]
- peptidyl-serine phosphorylation [IBA]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [ISS]
- protein phosphorylation [IDA, ISS]
- regulation of cell shape [IBA]
- regulation of circadian rhythm [ISS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.
Essentially all biological processes depend on protein-protein interactions (PPIs). Timing of such interactions is crucial for regulatory function. Although circadian (~24-hour) clocks constitute fundamental cellular timing mechanisms regulating important physiological processes, PPI dynamics on this timescale are largely unknown. Here, we identified 109 novel PPIs among circadian clock proteins via a yeast-two-hybrid approach. Among them, the interaction of protein phosphatase ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CSNK1E ARNTL | Biochemical Activity Biochemical Activity An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation. | Low | - | BioGRID | 277129 |
Curated By
- BioGRID