BAIT
BSG
5F7, CD147, EMMPRIN, M6, OK, TCSF, UNQ6505/PRO21383
basigin (Ok blood group)
GO Process (9)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cell surface receptor signaling pathway [TAS]
- cellular metabolic process [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- leukocyte migration [TAS]
- protein targeting to plasma membrane [ISS]
- pyruvate metabolic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
MYBBP1A
P160, PAP2
MYB binding protein (P160) 1a
GO Process (8)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- cellular response to glucose starvation [IDA]
- circadian regulation of gene expression [ISS]
- intrinsic apoptotic signaling pathway by p53 class mediator [IMP]
- negative regulation of transcription, DNA-templated [ISS]
- nucleocytoplasmic transport [ISS]
- osteoblast differentiation [IDA]
- positive regulation of cell cycle arrest [IMP]
- regulation of transcription, DNA-templated [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network: A Systematic Exploration of the Human Interactome.
Protein interactions form a network whose structure drives cellular function and whose organization informs biological inquiry. Using high-throughput affinity-purification mass spectrometry, we identify interacting partners for 2,594 human proteins in HEK293T cells. The resulting network (BioPlex) contains 23,744 interactions among 7,668 proteins with 86% previously undocumented. BioPlex accurately depicts known complexes, attaining 80%-100% coverage for most CORUM complexes. The network ... [more]
Cell Jul. 16, 2015; 162(2);425-40 [Pubmed: 26186194]
Quantitative Score
- 0.838216327 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 1.0 HEK 293T cells CompPASS score = 0.838216327, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 2.0 (PMID: 28514442) and BioPlex 3.0 (PMID: 33961781). Only scores from within BioPlex 1.0 (PMID: 26186194) should be compared directly.
Curated By
- BioGRID