EEF1G
Gene Ontology Biological Process
Gene Ontology Molecular Function
MKKS
Gene Ontology Biological Process
- brain morphogenesis [ISS]
- cerebral cortex development [ISS]
- cilium assembly [ISS]
- cilium morphogenesis [ISS]
- convergent extension involved in gastrulation [ISS]
- detection of mechanical stimulus involved in sensory perception of sound [ISS]
- determination of left/right symmetry [ISS]
- fat cell differentiation [ISS]
- gonad development [TAS]
- heart development [TAS]
- heart looping [ISS]
- hippocampus development [ISS]
- intracellular transport [ISS]
- melanosome transport [ISS]
- negative regulation of appetite by leptin-mediated signaling pathway [ISS]
- photoreceptor cell maintenance [ISS]
- pigment granule aggregation in cell center [ISS]
- regulation of cilium beat frequency involved in ciliary motility [ISS]
- sensory perception of smell [ISS]
- social behavior [ISS]
- spermatid development [ISS]
- striatum development [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The BioPlex Network: A Systematic Exploration of the Human Interactome.
Protein interactions form a network whose structure drives cellular function and whose organization informs biological inquiry. Using high-throughput affinity-purification mass spectrometry, we identify interacting partners for 2,594 human proteins in HEK293T cells. The resulting network (BioPlex) contains 23,744 interactions among 7,668 proteins with 86% previously undocumented. BioPlex accurately depicts known complexes, attaining 80%-100% coverage for most CORUM complexes. The network ... [more]
Quantitative Score
- 0.999979422 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 1.0 HEK 293T cells CompPASS score = 0.999979422, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 2.0 (PMID: 28514442) and BioPlex 3.0 (PMID: 33961781). Only scores from within BioPlex 1.0 (PMID: 26186194) should be compared directly.
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
EEF1G MKKS | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 2220903 | |
EEF1G MKKS | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9996 | BioGRID | 3071472 |
Curated By
- BioGRID