BAIT
EPS8
DFNB102
epidermal growth factor receptor pathway substrate 8
GO Process (13)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- Rac protein signal transduction [ISS]
- actin crosslink formation [ISS]
- actin filament bundle assembly [ISS]
- actin polymerization-dependent cell motility [ISS]
- barbed-end actin filament capping [ISS]
- cell proliferation [TAS]
- dendritic cell migration [ISS]
- epidermal growth factor receptor signaling pathway [TAS]
- exit from mitosis [ISS]
- positive regulation of signal transduction [TAS]
- regulation of actin filament length [ISS]
- regulation of cell shape [ISS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BLOC1S6
BLOS6, HPS9, PA, PALLID, PLDN
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
GO Process (10)
GO Function (5)
GO Component (7)
Gene Ontology Biological Process
- anterograde axon cargo transport [ISS]
- anterograde synaptic vesicle transport [ISS]
- endosome to melanosome transport [IDA]
- melanosome organization [NAS]
- melanosome transport [IDA]
- membrane organization [TAS]
- neuron projection development [ISS]
- positive regulation of pigment cell differentiation [IDA]
- post-Golgi vesicle-mediated transport [TAS]
- synaptic vesicle docking [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Towards a proteome-scale map of the human protein-protein interaction network.
Systematic mapping of protein-protein interactions, or 'interactome' mapping, was initiated in model organisms, starting with defined biological processes and then expanding to the scale of the proteome. Although far from complete, such maps have revealed global topological and dynamic features of interactome networks that relate to known biological properties, suggesting that a human interactome map will provide insight into development ... [more]
Nature Oct. 20, 2005; 437(7062);1173-8 [Pubmed: 16189514]
Throughput
- High Throughput
Curated By
- BioGRID