BAIT
ACTN1
BDPLT15
actinin, alpha 1
GO Process (8)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
GO Process (8)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- DNA ligation involved in DNA repair [IDA]
- DNA repair [TAS]
- double-strand break repair [IDA, TAS]
- double-strand break repair via nonhomologous end joining [IDA, IMP, NAS, TAS]
- establishment of integrated proviral latency [TAS]
- positive regulation of ligase activity [IDA]
- response to X-ray [IDA]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Towards a proteome-scale map of the human protein-protein interaction network.
Systematic mapping of protein-protein interactions, or 'interactome' mapping, was initiated in model organisms, starting with defined biological processes and then expanding to the scale of the proteome. Although far from complete, such maps have revealed global topological and dynamic features of interactome networks that relate to known biological properties, suggesting that a human interactome map will provide insight into development ... [more]
Nature Oct. 20, 2005; 437(7062);1173-8 [Pubmed: 16189514]
Throughput
- High Throughput
Curated By
- BioGRID