PSMC5
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest [TAS]
- G1/S transition of mitotic cell cycle [TAS]
- RNA metabolic process [TAS]
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- apoptotic process [TAS]
- cellular nitrogen compound metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- mitotic cell cycle [TAS]
- negative regulation of apoptotic process [TAS]
- negative regulation of programmed cell death [NAS]
- negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- positive regulation of transcription, DNA-templated [NAS]
- positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IDA]
- protein polyubiquitination [TAS]
- regulation of apoptotic process [TAS]
- regulation of cellular amino acid metabolic process [TAS]
- regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [TAS]
- small molecule metabolic process [TAS]
- transcription from RNA polymerase II promoter [TAS]
- viral process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
RORA
Gene Ontology Biological Process
- T-helper 17 cell differentiation [ISS]
- angiogenesis [IMP]
- cellular response to hypoxia [IMP]
- cellular response to sterol [IDA, IMP]
- cerebellar granule cell precursor proliferation [ISS]
- circadian regulation of gene expression [ISS]
- gene expression [TAS]
- intracellular receptor signaling pathway [IDA]
- muscle cell differentiation [IMP]
- negative regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- negative regulation of fat cell differentiation [ISS]
- negative regulation of inflammatory response [IMP]
- positive regulation of circadian rhythm [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- positive regulation vascular endothelial growth factor production [IMP]
- regulation of cholesterol homeostasis [ISS]
- regulation of glucose metabolic process [ISS]
- regulation of smoothened signaling pathway [ISS]
- regulation of steroid metabolic process [ISS]
- regulation of transcription involved in cell fate commitment [ISS]
- regulation of transcription, DNA-templated [IDA]
- transcription initiation from RNA polymerase II promoter [TAS]
- triglyceride homeostasis [IMP]
- xenobiotic metabolic process [ISS]
Gene Ontology Molecular Function- DNA binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- direct ligand regulated sequence-specific DNA binding transcription factor activity [IDA]
- oxysterol binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator binding [IPI]
- transcription corepressor binding [IPI]
- transcription factor binding [IPI]
- DNA binding [IDA]
- core promoter sequence-specific DNA binding [IDA]
- direct ligand regulated sequence-specific DNA binding transcription factor activity [IDA]
- oxysterol binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator binding [IPI]
- transcription corepressor binding [IPI]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
- nucleoplasm [TAS]
- nucleus [IDA]
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Towards a proteome-scale map of the human protein-protein interaction network.
Systematic mapping of protein-protein interactions, or 'interactome' mapping, was initiated in model organisms, starting with defined biological processes and then expanding to the scale of the proteome. Although far from complete, such maps have revealed global topological and dynamic features of interactome networks that relate to known biological properties, suggesting that a human interactome map will provide insight into development ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PSMC5 RORA | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - | |
| RORA PSMC5 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - | |
| RORA PSMC5 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | High | - | BioGRID | - |
Curated By
- BioGRID