BAIT
PS1
F22O13.18, F22O13_18, Presenilin-1, AT1G08700
Presenilin-1
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Arabidopsis thaliana (Columbia)
PREY
AT3G52640
Zn-dependent exopeptidases superfamily protein
GO Process (0)
GO Function (0)
GO Component (5)
Gene Ontology Cellular Component
Arabidopsis thaliana (Columbia)
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
Gamma-secretase subunits associate in intracellular membrane compartments in Arabidopsis thaliana.
Gamma-secretase is a multisubunit complex with intramembrane proteolytic activity. In humans it was identified in genetic screens of patients suffering from familial forms of Alzheimer's disease, and since then it was shown to mediate cleavage of more than 80 substrates, including amyloid precursor protein or Notch receptor. Moreover, in animals, γ-secretase was shown to be involved in regulation of a ... [more]
J. Exp. Bot. Jul. 01, 2014; 65(12);3015-27 [Pubmed: 24723404]
Throughput
- Low Throughput
Additional Notes
- BiFC assay
Curated By
- BioGRID