BAIT

IRC10

YOL015W
Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci
GO Process (0)
GO Function (0)
GO Component (1)

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)
PREY

ADY3

YDL239C
Protein required for spore wall formation; thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p; ADY3 has a paralog, CNM67, that arose from the whole genome duplication
GO Process (3)
GO Function (0)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)

Phenotypic Enhancement

A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

A visual screen of protein localization during sporulation identifies new components of prospore membrane-associated complexes in budding yeast.

Lam C, Santore E, Lavoie E, Needleman L, Fiacco N, Kim C, Neiman AM

During ascospore formation in Saccharomyces cerevisiae, the secretory pathway is reorganized to create new intracellular compartments, termed prospore membranes. Prospore membranes engulf the nuclei produced by the meiotic divisions, giving rise to individual spores. The shape and growth of prospore membranes are constrained by cytoskeletal structures, such as septin proteins, that associate with the membranes. Green fluorescent protein (GFP) fusions ... [more]

Eukaryotic Cell Mar. 01, 2014; 13(3);383-91 [Pubmed: 24390141]

Throughput

  • Low Throughput

Ontology Terms

  • sporulation efficiency (APO:0000044)

Additional Notes

  • Table 3
  • ady3 irc10 ykr015c yjl043w quadruple mutant has a sporulation defect
  • genetic complex

Curated By

  • BioGRID