BAIT
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
PRICKLE1
EPM1B, RILP
prickle homolog 1 (Drosophila)
GO Process (7)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- negative regulation of canonical Wnt signaling pathway [IDA]
- negative regulation of cardiac muscle cell myoblast differentiation [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- neural tube closure [IMP]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IDA]
- positive regulation of protein ubiquitination [IDA]
- protein import into nucleus [IDA, IMP]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.
Tissue homeostasis is controlled by signaling systems that coordinate cell proliferation, cell growth and cell shape upon changes in the cellular environment. Deregulation of these processes is associated with human cancer and can occur at multiple levels of the underlying signaling systems. To gain an integrated view on signaling modules controlling tissue growth, we analyzed the interaction proteome of the ... [more]
Mol. Syst. Biol. Dec. 25, 2013; 9(0);713 [Pubmed: 24366813]
Throughput
- High Throughput
Curated By
- BioGRID