BAIT

PAB2

ARABIDOPSIS POLY(A) BINDING 2, ATPAB2, F28A23.130, F28A23_130, PABP2, POLY(A) BINDING PROTEIN 2, POLY(A)-BINDING PROTEIN 2, AT4G34110
polyadenylate-binding protein 2
Arabidopsis thaliana (Columbia)
PREY

AT3G19090

RNA-binding protein
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Arabidopsis thaliana (Columbia)

Protein-peptide

An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.

Publication

The association of a La module with the PABP-interacting motif PAM2 is a recurrent evolutionary process that led to the neofunctionalization of La-related proteins.

Merret R, Martino L, Bousquet-Antonelli C, Fneich S, Descombin J, Billey E, Conte MR, Deragon JM

La-related proteins (LARPs) are largely uncharacterized factors, well conserved throughout evolution. Recent reports on the function of human LARP4 and LARP6 suggest that these proteins fulfill key functions in mRNA metabolism and/or translation. We report here a detailed evolutionary history of the LARP4 and 6 families in eukaryotes. Genes coding for LARP4 and 6 were duplicated in the common ancestor ... [more]

RNA Jan. 01, 2013; 19(1);36-50 [Pubmed: 23148093]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
AT3G19090 PAB2
Affinity Capture-Western
Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Low-BioGRID
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Curated By

  • BioGRID