BAIT

PCBP1

HEL-S-85, HNRPE1, HNRPX, hnRNP-E1, hnRNP-X
poly(rC) binding protein 1
GO Process (3)
GO Function (4)
GO Component (5)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

POLH

RAD30, RAD30A, XP-V, XPV, RP11-22I24.1
polymerase (DNA directed), eta
UPS Project
GO Process (4)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-RNA

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.

Publication

DNA polymerase η is regulated by poly(rC)-binding protein 1 via mRNA stability.

Ren C, Cho SJ, Jung YS, Chen X

POLH (DNA polymerase η), a target of p53 tumour suppressor, plays a key role in TLS (translesion DNA synthesis). Loss of POLH is responsible for the human cancer-prone syndrome XPV (xeroderma pigmentosum variant). Owing to its critical role in DNA repair and genome stability, POLH expression and activity are regulated by multiple pathways. In the present study, we found that ... [more]

Biochem. J. Dec. 15, 2014; 464(3);377-86 [Pubmed: 25268038]

Throughput

  • Low Throughput

Curated By

  • BioGRID