BAIT
PAIP1
poly(A) binding protein interacting protein 1
GO Process (8)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- mRNA stabilization [TAS]
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
- nuclear-transcribed mRNA poly(A) tail shortening [TAS]
- positive regulation of translation [IDA]
- translational initiation [TAS]
Gene Ontology Molecular Function
Homo sapiens
PREY
EIF3A
EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185
eukaryotic translation initiation factor 3, subunit A
GO Process (5)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Control of Paip1-eukayrotic translation initiation factor 3 interaction by amino acids through S6 kinase.
The simultaneous interaction of poly(A)-binding protein (PABP) with eukaryotic translation initiation factor 4G (eIF4G) and the mRNA 3' poly(A) tail promotes translation initiation. We previously showed that the interaction of PABP-interacting protein 1 (Paip1) with PABP and eukaryotic translation initiation factor 3 (eIF3; via the eIF3g subunit) further stimulates translation. Here, we demonstrate that the interaction of eIF3 with Paip1 ... [more]
Mol. Cell. Biol. Mar. 01, 2014; 34(6);1046-53 [Pubmed: 24396066]
Throughput
- Low Throughput
Curated By
- BioGRID