BAIT

RILP

PP10141
Rab interacting lysosomal protein
GO Process (3)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

VPS41

HVPS41, HVSP41, hVps41p
vacuolar protein sorting 41 homolog (S. cerevisiae)
Autophagy Project
UPS Project
Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking.

Lin X, Yang T, Wang S, Wang Z, Yun Y, Sun L, Zhou Y, Xu X, Akazawa C, Hong W, Wang T

The HOPS complex serves as a tethering complex with GEF activity for Ypt7p in yeast to regulate late endosomal membrane maturation. While the role of HOPS complex is well established in yeast cells, its functional and mechanistic aspects in mammalian cells are less well defined. In this study, we report that RILP, a downstream effector of Rab7, interacts with HOPS ... [more]

Sci Rep Dec. 03, 2014; 4(0);7282 [Pubmed: 25445562]

Throughput

  • Low Throughput

Curated By

  • BioGRID