EXOC5
Gene Ontology Biological Process
SEC61B
Gene Ontology Biological Process
- ER-associated ubiquitin-dependent protein catabolic process [IDA]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- protein import into nucleus, translocation [IMP]
- retrograde protein transport, ER to cytosol [IMP]
- translation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Exocyst Sec10 is involved in basolateral protein translation and translocation in the endoplasmic reticulum.
Protein translation and translocation at the rough endoplasmic reticulum (RER) are the first steps in the secretory pathway. The translocon through which newly made proteins are translocated into or across the RER membrane consists of three main subunits: Sec61α, -β, and -γ. Sec61β facilitates translocation, and we and others have shown that the highly conserved eight-protein exocyst complex interacts with ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID