BAIT
UBE2B
E2-17kDa, HHR6B, HR6B, RAD6B, UBC2
ubiquitin-conjugating enzyme E2B
GO Process (19)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- DNA repair [IGI]
- canonical Wnt signaling pathway [ISS]
- cellular response to DNA damage stimulus [IDA]
- histone H2A ubiquitination [IMP]
- negative regulation of cAMP-mediated signaling [IDA]
- postreplication repair [IDA, NAS]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IDA]
- protein K11-linked ubiquitination [IDA]
- protein K48-linked ubiquitination [IDA]
- protein K63-linked ubiquitination [IDA]
- protein autoubiquitination [IDA]
- protein monoubiquitination [IMP]
- protein polyubiquitination [IMP]
- protein stabilization [IMP]
- protein ubiquitination [IDA]
- response to UV [IGI]
- response to drug [IDA]
- spermatogenesis [TAS]
- ubiquitin-dependent protein catabolic process [IDA, NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SSBP1
Mt-SSB, SOSS-B1, SSBP, mtSSB
single-stranded DNA binding protein 1, mitochondrial
GO Process (1)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and lysosome-mediated degradation.
RAD6 is a ubiquitin E2 protein with roles in a number of different biological processes. Here, using affinity purification coupled with mass spectrometry, we identify a number of new RAD6 binding partners, including the poorly characterized ubiquitin E3 ligases KCMF1 (potassium channel modulatory factor 1) and UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4), a protein that can bind N-end rule ... [more]
Mol. Cell Proteomics Mar. 01, 2015; 14(3);674-85 [Pubmed: 25582440]
Throughput
- High Throughput
Curated By
- BioGRID