BAIT
UNK
B230379M23Rik, Zc3h5, Zc3hdc5, mKIAA1753, RP23-42F6.4
unkempt homolog (Drosophila)
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
ACTR3
1200003A09Rik, Arp3
ARP3 actin-related protein 3
GO Process (14)
GO Function (3)
GO Component (14)
Gene Ontology Biological Process
- Arp2/3 complex-mediated actin nucleation [ISO]
- asymmetric cell division [IGI]
- cilium morphogenesis [ISO]
- establishment or maintenance of cell polarity [IGI]
- meiotic cell cycle [IGI]
- meiotic chromosome movement towards spindle pole [IGI]
- meiotic cytokinesis [IGI]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of dendrite morphogenesis [ISO]
- positive regulation of filopodium assembly [ISO]
- positive regulation of lamellipodium assembly [ISO]
- positive regulation of neuron differentiation [ISO]
- regulation of myosin II filament organization [ISO]
- spindle localization [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.
Cellular morphology is an essential determinant of cellular function in all kingdoms of life, yet little is known about how cell shape is controlled. Here we describe a molecular program that controls the early morphology of neurons through a metazoan-specific zinc finger protein, Unkempt. Depletion of Unkempt in mouse embryos disrupts the shape of migrating neurons, while ectopic expression confers ... [more]
Genes Dev. Mar. 01, 2015; 29(5);501-12 [Pubmed: 25737280]
Throughput
- High Throughput
Curated By
- BioGRID