BAIT
UNK
B230379M23Rik, Zc3h5, Zc3hdc5, mKIAA1753, RP23-42F6.4
unkempt homolog (Drosophila)
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
YWHAE
AU019196, RP23-78H4.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
GO Process (8)
GO Function (12)
GO Component (6)
Gene Ontology Biological Process
- cerebral cortex development [IMP]
- hippocampus development [IMP]
- negative regulation of peptidyl-serine dephosphorylation [ISO]
- negative regulation of protein dephosphorylation [IDA]
- neuron migration [IGI, IMP]
- protein targeting [IDA]
- regulation of membrane repolarization [ISO]
- regulation of potassium ion transmembrane transporter activity [ISO]
Gene Ontology Molecular Function- MHC class II protein complex binding [ISO]
- enzyme binding [ISO]
- histone deacetylase binding [ISO]
- ion channel binding [ISO]
- phosphoprotein binding [ISO]
- phosphoserine binding [ISO]
- poly(A) RNA binding [ISO]
- potassium channel regulator activity [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [IDA]
- protein heterodimerization activity [ISO]
- MHC class II protein complex binding [ISO]
- enzyme binding [ISO]
- histone deacetylase binding [ISO]
- ion channel binding [ISO]
- phosphoprotein binding [ISO]
- phosphoserine binding [ISO]
- poly(A) RNA binding [ISO]
- potassium channel regulator activity [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [IDA]
- protein heterodimerization activity [ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.
Cellular morphology is an essential determinant of cellular function in all kingdoms of life, yet little is known about how cell shape is controlled. Here we describe a molecular program that controls the early morphology of neurons through a metazoan-specific zinc finger protein, Unkempt. Depletion of Unkempt in mouse embryos disrupts the shape of migrating neurons, while ectopic expression confers ... [more]
Genes Dev. Mar. 01, 2015; 29(5);501-12 [Pubmed: 25737280]
Throughput
- High Throughput
Curated By
- BioGRID