BAIT
UNK
B230379M23Rik, Zc3h5, Zc3hdc5, mKIAA1753, RP23-42F6.4
unkempt homolog (Drosophila)
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
ATP2A2
9530097L16Rik, D5Wsu150e, SERCA2, SERCA2B, mKIAA4195
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
GO Process (22)
GO Function (9)
GO Component (13)
Gene Ontology Biological Process
- ATP catabolic process [IDA, ISO]
- ER-nucleus signaling pathway [IMP]
- T-tubule organization [IMP]
- calcium ion import into sarcoplasmic reticulum [ISO]
- calcium ion transmembrane transport [IDA, ISO]
- calcium ion transport [ISO]
- calcium ion transport from cytosol to endoplasmic reticulum [ISO]
- cellular calcium ion homeostasis [IDA, IGI, IMP, ISO]
- endoplasmic reticulum calcium ion homeostasis [ISO]
- negative regulation of heart contraction [IGI]
- organelle organization [IMP]
- positive regulation of endoplasmic reticulum calcium ion concentration [ISO]
- regulation of calcium ion-dependent exocytosis of neurotransmitter [IMP]
- regulation of cardiac muscle cell action potential involved in regulation of contraction [ISO]
- regulation of cardiac muscle cell membrane potential [ISO]
- regulation of cardiac muscle contraction by calcium ion signaling [ISO]
- regulation of muscle contraction [TAS]
- regulation of the force of heart contraction [IGI]
- relaxation of cardiac muscle [ISO]
- response to peptide hormone [ISO]
- sarcoplasmic reticulum calcium ion transport [IMP, ISO]
- transition between fast and slow fiber [IDA]
Gene Ontology Molecular Function- ATP binding [ISO]
- S100 protein binding [ISO]
- calcium ion binding [ISO]
- calcium-transporting ATPase activity [IDA, ISO]
- calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential [ISO]
- enzyme binding [IPI, ISO]
- lutropin-choriogonadotropic hormone receptor binding [ISO]
- protein C-terminus binding [IPI, ISO]
- protein binding [IPI]
- ATP binding [ISO]
- S100 protein binding [ISO]
- calcium ion binding [ISO]
- calcium-transporting ATPase activity [IDA, ISO]
- calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential [ISO]
- enzyme binding [IPI, ISO]
- lutropin-choriogonadotropic hormone receptor binding [ISO]
- protein C-terminus binding [IPI, ISO]
- protein binding [IPI]
Gene Ontology Cellular Component
- calcium ion-transporting ATPase complex [ISO]
- cell [IGI]
- endoplasmic reticulum [IDA, ISO]
- endoplasmic reticulum membrane [ISO]
- extrinsic component of cytoplasmic side of plasma membrane [ISO]
- intercalated disc [ISO]
- longitudinal sarcoplasmic reticulum [ISO]
- membrane [IDA, ISO]
- perinuclear region of cytoplasm [ISO]
- protein complex [ISO]
- ribbon synapse [IDA]
- sarcoplasmic reticulum [IDA, ISO, TAS]
- vesicle membrane [ISO]
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.
Cellular morphology is an essential determinant of cellular function in all kingdoms of life, yet little is known about how cell shape is controlled. Here we describe a molecular program that controls the early morphology of neurons through a metazoan-specific zinc finger protein, Unkempt. Depletion of Unkempt in mouse embryos disrupts the shape of migrating neurons, while ectopic expression confers ... [more]
Genes Dev. Mar. 01, 2015; 29(5);501-12 [Pubmed: 25737280]
Throughput
- High Throughput
Curated By
- BioGRID