BAIT
UNK
B230379M23Rik, Zc3h5, Zc3hdc5, mKIAA1753, RP23-42F6.4
unkempt homolog (Drosophila)
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
RPS3
D7Ertd795e, Rs_3
ribosomal protein S3
GO Process (7)
GO Function (11)
GO Component (12)
Gene Ontology Biological Process
- DNA catabolic process, endonucleolytic [IBA, ISO]
- DNA repair [IBA]
- cytoplasmic translation [IBA]
- negative regulation of DNA repair [ISO]
- positive regulation of DNA N-glycosylase activity [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of apoptotic signaling pathway [ISO]
Gene Ontology Molecular Function- DNA-(apurinic or apyrimidinic site) lyase activity [ISO]
- NF-kappaB binding [ISO]
- damaged DNA binding [IBA, ISO]
- enzyme binding [ISO]
- mRNA binding [ISO]
- oxidized purine nucleobase lesion DNA N-glycosylase activity [IBA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase A binding [ISO]
- protein kinase binding [ISO]
- structural constituent of ribosome [IBA, ISO]
- DNA-(apurinic or apyrimidinic site) lyase activity [ISO]
- NF-kappaB binding [ISO]
- damaged DNA binding [IBA, ISO]
- enzyme binding [ISO]
- mRNA binding [ISO]
- oxidized purine nucleobase lesion DNA N-glycosylase activity [IBA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein kinase A binding [ISO]
- protein kinase binding [ISO]
- structural constituent of ribosome [IBA, ISO]
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.
Cellular morphology is an essential determinant of cellular function in all kingdoms of life, yet little is known about how cell shape is controlled. Here we describe a molecular program that controls the early morphology of neurons through a metazoan-specific zinc finger protein, Unkempt. Depletion of Unkempt in mouse embryos disrupts the shape of migrating neurons, while ectopic expression confers ... [more]
Genes Dev. Mar. 01, 2015; 29(5);501-12 [Pubmed: 25737280]
Throughput
- High Throughput
Curated By
- BioGRID