BAIT
UNK
B230379M23Rik, Zc3h5, Zc3hdc5, mKIAA1753, RP23-42F6.4
unkempt homolog (Drosophila)
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
RAP1A
AI848598, G-22K, Krev-1, Rap1
RAS-related protein-1a
GO Process (15)
GO Function (6)
GO Component (10)
Gene Ontology Biological Process
- GTP catabolic process [IDA]
- Rap protein signal transduction [ISO]
- cellular response to cAMP [ISO]
- cellular response to nerve growth factor stimulus [ISO]
- establishment of endothelial barrier [ISO]
- negative regulation of synaptic vesicle exocytosis [IGI]
- nerve growth factor signaling pathway [ISO]
- positive regulation of ERK1 and ERK2 cascade [IGI, ISO]
- positive regulation of Rap GTPase activity [ISO]
- positive regulation of neuron projection development [IDA, ISO]
- positive regulation of protein kinase activity [ISO]
- positive regulation of vasculogenesis [IMP]
- protein transport [ISO]
- regulation of cell junction assembly [ISO]
- small GTPase mediated signal transduction [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.
Cellular morphology is an essential determinant of cellular function in all kingdoms of life, yet little is known about how cell shape is controlled. Here we describe a molecular program that controls the early morphology of neurons through a metazoan-specific zinc finger protein, Unkempt. Depletion of Unkempt in mouse embryos disrupts the shape of migrating neurons, while ectopic expression confers ... [more]
Genes Dev. Mar. 01, 2015; 29(5);501-12 [Pubmed: 25737280]
Throughput
- High Throughput
Curated By
- BioGRID