BAIT
UNK
B230379M23Rik, Zc3h5, Zc3hdc5, mKIAA1753, RP23-42F6.4
unkempt homolog (Drosophila)
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
MTMR2
6030445P13Rik, RP23-133A3.2
myotubularin related protein 2
GO Process (14)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- dendritic spine maintenance [ISO]
- dephosphorylation [IDA, IMP]
- inositol phosphate dephosphorylation [IDA]
- myelin assembly [IGI, IMP]
- negative regulation of endocytosis [ISO]
- negative regulation of excitatory postsynaptic membrane potential [ISO]
- negative regulation of myelination [IGI]
- negative regulation of receptor catabolic process [ISO]
- negative regulation of receptor internalization [ISO]
- neuron development [IGI]
- phosphatidylinositol dephosphorylation [IDA, ISO]
- phosphatidylinositol metabolic process [IMP]
- positive regulation of early endosome to late endosome transport [ISO]
- protein tetramerization [IPI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.
Cellular morphology is an essential determinant of cellular function in all kingdoms of life, yet little is known about how cell shape is controlled. Here we describe a molecular program that controls the early morphology of neurons through a metazoan-specific zinc finger protein, Unkempt. Depletion of Unkempt in mouse embryos disrupts the shape of migrating neurons, while ectopic expression confers ... [more]
Genes Dev. Mar. 01, 2015; 29(5);501-12 [Pubmed: 25737280]
Throughput
- High Throughput
Curated By
- BioGRID