BAIT
UNK
B230379M23Rik, Zc3h5, Zc3hdc5, mKIAA1753, RP23-42F6.4
unkempt homolog (Drosophila)
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
WAC
1110067P07Rik, A230035H12Rik, AI256735, AI256776, Wwp4
WW domain containing adaptor with coiled-coil
GO Process (7)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- G1 DNA damage checkpoint [ISO]
- cellular response to DNA damage stimulus [ISO]
- histone H2B conserved C-terminal lysine ubiquitination [ISO]
- histone monoubiquitination [ISO]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO]
- positive regulation of macroautophagy [ISO]
- positive regulation of transcription, DNA-templated [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.
Cellular morphology is an essential determinant of cellular function in all kingdoms of life, yet little is known about how cell shape is controlled. Here we describe a molecular program that controls the early morphology of neurons through a metazoan-specific zinc finger protein, Unkempt. Depletion of Unkempt in mouse embryos disrupts the shape of migrating neurons, while ectopic expression confers ... [more]
Genes Dev. Mar. 01, 2015; 29(5);501-12 [Pubmed: 25737280]
Throughput
- High Throughput
Curated By
- BioGRID