BAIT
UNK
B230379M23Rik, Zc3h5, Zc3hdc5, mKIAA1753, RP23-42F6.4
unkempt homolog (Drosophila)
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
HMGCR
HMG-CoAR, Red
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
GO Process (19)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
- cholesterol biosynthetic process [IDA, ISO]
- embryo development [IMP]
- isoprenoid biosynthetic process [ISO]
- negative regulation of MAP kinase activity [IGI]
- negative regulation of apoptotic process [ISO]
- negative regulation of insulin secretion involved in cellular response to glucose stimulus [ISO]
- negative regulation of striated muscle cell apoptotic process [ISO]
- negative regulation of vasodilation [ISO]
- negative regulation of wound healing [ISO]
- oxidation-reduction process [ISO]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of cardiac muscle cell apoptotic process [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of skeletal muscle tissue development [ISO]
- positive regulation of smooth muscle cell proliferation [ISO]
- positive regulation of stress-activated MAPK cascade [ISO]
- protein tetramerization [ISO]
- ubiquinone metabolic process [ISO]
- visual learning [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.
Cellular morphology is an essential determinant of cellular function in all kingdoms of life, yet little is known about how cell shape is controlled. Here we describe a molecular program that controls the early morphology of neurons through a metazoan-specific zinc finger protein, Unkempt. Depletion of Unkempt in mouse embryos disrupts the shape of migrating neurons, while ectopic expression confers ... [more]
Genes Dev. Mar. 01, 2015; 29(5);501-12 [Pubmed: 25737280]
Throughput
- High Throughput
Curated By
- BioGRID