BAIT
PRICKLE1
EPM1B, RILP
prickle homolog 1 (Drosophila)
GO Process (7)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- negative regulation of canonical Wnt signaling pathway [IDA]
- negative regulation of cardiac muscle cell myoblast differentiation [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- neural tube closure [IMP]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IDA]
- positive regulation of protein ubiquitination [IDA]
- protein import into nucleus [IDA, IMP]
Gene Ontology Molecular Function
Homo sapiens
PREY
TANC1
Tanc
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Seizures are regulated by ubiquitin-specific peptidase 9 X-linked (USP9X), a de-ubiquitinase.
Epilepsy is a common disabling disease with complex, multifactorial genetic and environmental etiology. The small fraction of epilepsies subject to Mendelian inheritance offers key insight into epilepsy disease mechanisms; and pathologies brought on by mutations in a single gene can point the way to generalizable therapeutic strategies. Mutations in the PRICKLE genes can cause seizures in humans, zebrafish, mice, and ... [more]
PLoS Genet. Mar. 01, 2015; 11(3);e1005022 [Pubmed: 25763846]
Throughput
- Low Throughput
Curated By
- BioGRID