BAIT
MX1
IFI-78K, IFI78, MX, MxA
MX dynamin-like GTPase 1
GO Process (9)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KIF26B
hCG_21329
kinesin family member 26B
GO Process (2)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
MxA interacts with and is modified by the SUMOylation machinery.
Mx proteins are evolutionarily conserved dynamin-like large GTPases involved in viral resistance triggered by types I and III interferons. The human MxA is a cytoplasmic protein that confers resistance to a large number of viruses. The MxA protein is also known to self-assembly into high molecular weight homo-oligomers. Using a yeast two-hybrid screen, we identified 27 MxA binding partners, some ... [more]
Exp. Cell Res. Jan. 01, 2015; 330(1);151-63 [Pubmed: 25447205]
Throughput
- Low Throughput
Curated By
- BioGRID