Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

MxA interacts with and is modified by the SUMOylation machinery.

Brantis-de-Carvalho CE, Maarifi G, Goncalves Boldrin PE, Zanelli CF, Nisole S, Chelbi-Alix MK, Valentini SR

Mx proteins are evolutionarily conserved dynamin-like large GTPases involved in viral resistance triggered by types I and III interferons. The human MxA is a cytoplasmic protein that confers resistance to a large number of viruses. The MxA protein is also known to self-assembly into high molecular weight homo-oligomers. Using a yeast two-hybrid screen, we identified 27 MxA binding partners, some ... [more]

Exp. Cell Res. Jan. 01, 2015; 330(1);151-63 [Pubmed: 25447205]

Throughput

Low Throughput

Curated By

BioGRID

Interaction Summary

MX1

Gene Ontology Biological Process

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

ZCCHC12