BAIT
SCARNA22
ACA11
small Cajal body-specific RNA 22
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
ARHGAP4
C1, RGC1, RhoGAP4, SrGAP4, p115
Rho GTPase activating protein 4
GO Process (8)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- Rho protein signal transduction [TAS]
- apoptotic signaling pathway [TAS]
- cytoskeleton organization [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- positive regulation of apoptotic process [TAS]
- positive regulation of signal transduction [TAS]
- regulation of small GTPase mediated signal transduction [TAS]
- small GTPase mediated signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.
The histone methyltransferase WHSC1 (also known as MMSET) is overexpressed in multiple myeloma (MM) as a result of the t(4;14) chromosomal translocation and in a broad variety of other cancers by unclear mechanisms. Overexpression of WHSC1 did not transform wild-type or tumor-prone primary hematopoietic cells. We found that ACA11, an orphan box H/ACA class small nucleolar RNA (snoRNA) encoded within ... [more]
J. Clin. Invest. Aug. 01, 2012; 122(8);2793-806 [Pubmed: 22751105]
Throughput
- High Throughput
Curated By
- BioGRID