ILK
Gene Ontology Biological Process
- Schwann cell development [IMP]
- branching involved in ureteric bud morphogenesis [IDA]
- cell aging [ISO]
- cell cycle arrest [ISO]
- cell projection organization [IMP]
- establishment or maintenance of epithelial cell apical/basal polarity [IMP]
- extracellular fibril organization [ISO]
- fibroblast migration [IMP]
- integrin-mediated signaling pathway [ISO]
- myelin assembly [ISO]
- myelination in peripheral nervous system [IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of cardiac muscle cell apoptotic process [ISO]
- negative regulation of neural precursor cell proliferation [IGI, IMP]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of protein kinase activity [ISO]
- negative regulation of smooth muscle cell migration [ISO]
- negative regulation of smooth muscle cell proliferation [ISO]
- nerve development [IMP]
- neuron projection morphogenesis [ISO]
- peptidyl-serine phosphorylation [IMP, ISO]
- platelet aggregation [ISO]
- positive regulation of BMP signaling pathway [IMP]
- positive regulation of MAP kinase activity [ISO]
- positive regulation of MAPK cascade [ISO]
- positive regulation of axon extension [ISO]
- positive regulation of axonogenesis [ISO]
- positive regulation of canonical Wnt signaling pathway [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [IMP, ISO]
- positive regulation of cell-matrix adhesion [ISO]
- positive regulation of dendrite morphogenesis [ISO]
- positive regulation of myoblast differentiation [ISO]
- positive regulation of osteoblast differentiation [IMP]
- positive regulation of phosphorylation [ISO]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- protein heterooligomerization [ISO]
- protein kinase B signaling [IMP]
- protein phosphorylation [ISO]
- regulation of actin cytoskeleton organization [ISO]
- regulation of cell growth [ISO]
- substrate adhesion-dependent cell spreading [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [ISO]
- cell junction [ISO]
- cell-cell junction [ISO]
- costamere [ISO]
- cytoplasm [ISO]
- dendritic shaft [ISO]
- extracellular matrix [ISO]
- focal adhesion [IDA, ISA, ISO]
- intracellular [IMP]
- lamellipodium [IDA]
- membrane [ISO]
- neuronal cell body [ISO]
- nucleoplasm [ISO]
- protein complex [ISO]
- stress fiber [ISO]
- terminal bouton [ISO]
MBP
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Biochemical Activity (Phosphorylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Krueppel-like factor 5 controls keratinocyte migration via the integrin-linked kinase.
Migration of epithelial cells is critical for normal homeostasis in gut and skin, but the factors regulating this process are not completely understood. The zinc finger transcription factor Klf5 (IKLF; BTEB2) is highly expressed in proliferating cells of esophagus, skin, and other organs. We hypothesized that Klf5 regulates keratinocyte migration via the integrin-linked kinase (ILK), which, like Klf5, is localized ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID