TOPP4
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GAI
Gene Ontology Biological Process
- gibberellic acid mediated signaling pathway [TAS]
- hyperosmotic salinity response [IGI]
- jasmonic acid mediated signaling pathway [IGI]
- negative regulation of gibberellic acid mediated signaling pathway [IMP, TAS]
- negative regulation of seed germination [IGI]
- phloem transport [IMP]
- regulation of nitrogen utilization [IMP]
- regulation of reactive oxygen species metabolic process [IGI]
- regulation of seed dormancy process [IGI]
- regulation of seed germination [IGI]
- response to abscisic acid [IGI]
- response to ethylene [IGI]
- response to far red light [IEP]
- response to gibberellin [IEP]
- response to salt stress [IGI]
- salicylic acid mediated signaling pathway [IGI]
Gene Ontology Molecular Function
Biochemical Activity (Dephosphorylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Arabidopsis DELLA protein degradation is controlled by a type-one protein phosphatase, TOPP4.
Gibberellins (GAs) are a class of important phytohormones regulating a variety of physiological processes during normal plant growth and development. One of the major events during GA-mediated growth is the degradation of DELLA proteins, key negative regulators of GA signaling pathway. The stability of DELLA proteins is thought to be controlled by protein phosphorylation and dephosphorylation. Up to date, no ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TOPP4 GAI | PCA PCA A Protein-Fragment Complementation Assay (PCA) is a protein-protein interaction assay in which a bait protein is expressed as fusion to one of the either N- or C- terminal peptide fragments of a reporter protein and prey protein is expressed as fusion to the complementary N- or C- terminal fragment of the same reporter protein. Interaction of bait and prey proteins bring together complementary fragments, which can then fold into an active reporter, e.g. the split-ubiquitin assay. | Low | - | BioGRID | - | |
| TOPP4 GAI | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - | |
| TOPP4 GAI | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID