BAIT
CLIP2
CLIP-115, Cyln2
CAP-GLY domain containing linker protein 2
GO Process (1)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
CLASP1
1700030C23Rik, 5730583A19Rik, B130045P17Rik, CLASP1alpha
CLIP associating protein 1
GO Process (10)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- cell division [ISO]
- establishment of spindle orientation [ISO]
- exit from mitosis [ISO]
- microtubule anchoring [ISO]
- microtubule bundle formation [ISO]
- microtubule cytoskeleton organization [ISO]
- microtubule nucleation [ISO]
- microtubule organizing center organization [ISO]
- negative regulation of microtubule depolymerization [IDA, ISO]
- negative regulation of microtubule polymerization or depolymerization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.
CLIP-170 and CLIP-115 are cytoplasmic linker proteins that associate specifically with the ends of growing microtubules and may act as anti-catastrophe factors. Here, we have isolated two CLIP-associated proteins (CLASPs), which are homologous to the Drosophila Orbit/Mast microtubule-associated protein. CLASPs bind CLIPs and microtubules, colocalize with the CLIPs at microtubule distal ends, and have microtubule-stabilizing effects in transfected cells. After ... [more]
Cell Mar. 23, 2001; 104(6);923-35 [Pubmed: 11290329]
Throughput
- Low Throughput
Additional Notes
- Figure 1
Curated By
- BioGRID